WHAT IS THYROID FUNCTION TEST ??





What is Thyroid ?


    The Thyroid is a small gland located in the lower-front part of your neck. It’s responsible for helping regulate many bodily processes, such as metabolism, energy generation, and mood.

The thyroid produces two major hormones: triiodothyronine (T3) and thyroxine (T4)


If your thyroid gland doesn’t produce enough of these hormones, you may experience symptoms such as weight gain, lack of energy, and depression. This condition is called hypothyroidism.


If your thyroid gland produces too many hormones, you may experience weight loss, high levels of anxiety, tremors, and a sense of being on a high. This is called hyperthyroidism.


How can Thyroid function be investigated? 

     Tests for investigation of Thyroid dysfunction can be separated into Two categories They are :-

Tests to established Thyroid status :-

Measurement of TSH in Plasma or Serum Measurements of Thyroid Hormones {T4 and T3} in Plasma or Serum


Tests to elucidate cause of Thyroid dysfunction :-

Thyroid Auto-antibody

Serum Thyroglobulin

Thyroid Peroxidase

Biopsy of the Thyroid

Ultrasound and Isotopic Thyroid Scanning


Any Preparing for the tests ?

      You don’t need to do anything special to prepare for the thyroid function tests.

If a healthcare professional has ordered other blood tests to be taken at the same time, you may need to fast for several hours before the test. They will let you know of any special instructions to follow.

Otherwise, you will not need to follow any specific directions before the test.


What tests are used to determine Thyroid status? 

Thyroid-Stimulating Hormone (TSH): 

Single most sensitive, specific and reliable test of Thyroid status in both overt and subclinical thyroid dysfunction

 Can be used to diagnose Primary Hypothyroidism

Can be used to differentiate Primary from Secondary Hypothyroidism

Thyroid-Releasing Hormone (TRH):

Test to evaluate patients with Hyperthyroidism and Hypothyroidism

Helpful in differential diagnosis of Hypothyroidism

Free Thyroxine (FT4):

 Used to evaluate Thyroid Function

 Used to diagnose Hyperthyroidism or Hypothyroidism

 Free Triiodothyronine (F T3):

 Used to diagnose Thyroid Function

 Used to monitor replacement and suppressive thyroid therapy

Thyroxine (Total T4):

Used in assessing Thyroid Function

Used to monitor Replacement and Suppressive Therapy

Total Triiodothyronine (Total T3): 

 Used to evaluate Thyroid Function

Mainly used to diagnose Hyperthyroidism Used to monitor Replacement and Suppressive therapy



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